Indications of Napa Extra 500 mg 65 mg

In the situation described below, Napa Extra 500 mg 65 mg is indicated: Headache Migraine Toothache Neuralgia Feverishness Period pain Sore throat Backache Help to reduce the temperature Aches and pain of colds and flu

Theropeutic Class

Non opioid analgesics

Pharmacology

Napa Extra 500 mg 65 mg is the result of mixing caffeine with paracetamol (acetaminophen). It has antipyretic and analgesic qualities. The analgesic action of paracetamol is enhanced by caffeine. One of the most popular and safest analgesics and antipyretics is paracetamol. It acts as an analgesic by lowering the pain threshold and as an antipyretic by affecting the hypothalamus heat regulatory area. An alkaloid similar to theophylline and Xanthine, caffeine is a stimulant. Caffeine improves the solubility and transmembrane permeability of paracetamol through intermolecular interaction with it. Caffeine also raises one's pain tolerance and pain threshold. Another advantage of caffeine for the treatment of migraine and headaches is its inherent ability to increase cerebral blood vessel tone.

Dosage and Administration of Napa Extra 500 mg 65 mg

Adult dose: 1-2 tablets every 4-6 hours. Maximum dose: 8 tablets daily. Child dose: Not recommended for children below 12 years.

Dosage of Napa Extra 500 mg 65 mg

Adult dose: 1-2 tablets every 4-6 hours. Maximum dose: 8 tablets daily. Child dose: Not recommended for children below 12 years.

Interaction of Napa Extra 500 mg 65 mg

Anticonvulsants may lower serum levels (e.g. phenytoin, barbiturates, carbamazepine). Warfarin and other coumarins' anticoagulant effects may be strengthened by extended use. increased absorption of domperidone with metoclopramide. Probenecid may lead to an increase in serum levels. Chloramphenicol serum concentrations might rise. Colestyramine within 1 hour of administration may decrease absorption. Phenothiazine may significantly increase hypothermia.

Contraindications

Those with severe renal function impairment and hepatic illness should not use paracetamol (Viral Hepatitis). known sensitivity to caffeine or aspirin.

Side Effects of Napa Extra 500 mg 65 mg

Although hematological responses such as thrombocytopenia, leukopenia, pancytopenia, neutropenia, and agranulocytosis have been described, paracetamol side effects are typically moderate. There are sporadic cases of pancreatitis, skin rashes, and other adverse responses.

Pregnancy and Lactation

Doctors should be consulted before pregnant women take caffeine and paracetamol. It is safe to take caffeine and paracetamol during breastfeeding.

Precautions and Warnings

The following situations necessitate cautious administration of caffeine and paracetamol: While taking additional hepatotoxic medications by patients with hepatic or renal impairment. Avoid using the medicine for an extended period of time without first consulting a doctor.

Overdose Effects of Napa Extra 500 mg 65 mg

Pallor, nausea, vomiting, anorexia, and stomach discomfort are the initial 24-hour paracetamol overdose symptoms. 12 to 40 hours after intake, liver damage might be noticed. There may be metabolic acidosis and abnormalities in glucose metabolism.

Storage Conditions

Keep away from light and moisture in a cool, dry location. Keep all medications out of the children's reach.

Drug Classes

Non opioid analgesics

Mode Of Action

Napa Extra 500 mg 65 mg contains both caffeine and paracetamol. The antipyretic and analgesic effects of paracetamol are combined with a negligible anti-inflammatory effect. A xanthine derivative that resembles theophylline, caffeine is an alkaloid. Caffeine improves the solubility and transmembrane permeability of paracetamol through intermolecular interaction with it. Coffee also raises one's pain tolerance and pain threshold. Another advantage of caffeine for treating migraines and headaches is its inherent ability to increase brain vascular tone.

Pregnancy

Doctors should be consulted before pregnant women take caffeine and paracetamol. It is safe to take caffeine and paracetamol during breastfeeding.