Indications of Zifolet 5 mg 20 mg

This tablet is indicated for the treatment and prophylaxis of Folic Acid and Zinc deficiencies.

Theropeutic Class

Specific mineral and vitamin combined preparations

Pharmacology

Zinc is an essential element in human health with a wide range of roles. It works as a coenzyme for more than 200 enzymes. These enzymes are involved in nucleic acid and protein metabolism and the production of energy. Zinc is vital for growth and development. Zinc deficiency can result in growth retardation, immune dysfunction, increased incidence of infections, anorexia, weight loss, neural tube defects of the foetus, increased risk for abortion and mental lethargy. Folic Acid is the member of B-vitamin group. Folic Acid participates in several key biological processes, including the synthesis of DNA, RNA and proteins. It is necessary for DNA replication and is involved in the regulation of gene expression. Folic Acid deficiency in pregnant women results in an increased incidence of neural tube defects, including meningomyelocele (e.g., spina bifida), anencephaly, meningocele and craniorachischisis in their neonates. Folic Acid deficiency leads to megaloblastic anemia. Other symptoms and signs of Folic Acid deficiency include weakness, fatigue, irritability, headache, difficulty concentrating, palpitations etc.

Dosage and Administration of Zifolet 5 mg 20 mg

One tablet daily or as recommended by the physician.

Dosage of Zifolet 5 mg 20 mg

Orally 1 tablet daily or as directed by the physician.

Interaction of Zifolet 5 mg 20 mg

A large amount of Calcium decreases the absorption of Zinc. In case of Folic Acid, no drug interactions have been reported.

Contraindications

Zinc is contraindicated in patients having hypersensitivity to Zinc. Folic Acid is contraindicated in untreated cobalamine deficiency

Side Effects of Zifolet 5 mg 20 mg

Folic Acid and Zinc is well tolerated in the recommended dose. Occasionally gastrointestinal disturbances like abdominal pain, dyspepsia, nausea, vomiting, fever and respiratory distress may occur.

Pregnancy and Lactation

Use in pregnancy and lactation: Recommended

Overdose Effects of Zifolet 5 mg 20 mg

Zinc Sulfate is corrosive in overdose. Symptoms are corrosion and inflammation of the mucous membrane of the mouth and stomach.

Storage Conditions

Store at temperature of below 30°C, protect from light and moisture. Keep out of reach of children.

Drug Classes

Specific mineral and vitamin combined preparations

Mode Of Action

This tablet is a special preparation of Folic Acid and Zinc Sulfate Monohydrate. Zinc is an essential trace element required for human nutrition and involved in a number of body enzyme system. Severe Zinc deficiency causes skin lesion, alopecia, diarrhoea, increased susceptibility of infections, cognitive impairment, etc. Folic Acid is a member of the B-Vitamins group. It is reduced in the body to tetrahydrofolate, which is the coenzyme for various metabolic processes including the synthesis of purine and pyrimidine nucleotides, and hence the synthesis of DNA. It is also involved in some amino acid conversions. Deficiency of Folic Acid may cause megaloblastic anaemia, develops when the dietary intake is inadequate, as in malnutrition, from malabsorption, from increased utilization as in pregnancy of conditions such as haemolytic anaemia, and as a result of administration of folate antagonists.

Pregnancy

Recommended during pregnancy and lactation.

Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.