Medicine overview
Indications of Acitrin 10 mg
Acitrin 10 mg indicated for the relief of symptoms associated with seasonal and perennial allergic rhinitis. It is also indicated for the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria and allergen induced asthma.

Theropeutic Class
Sedating Anti-histamine

Pharmacology
Acitrin 10 mg is a potent H1 receptor antagonist without any significant anticholinergic and antiserotonic effects. At pharmacologically active dose levels, it has almost no drowsiness effect and does not cause behavioural changes. It inhibits the histamine mediated early phase of the allergic reaction and also reduces the migration of inflammatory cells and the release of mediators associated with the late phase of the allergic reaction.

Dosage and Administration of Acitrin 10 mg
Adults and Children 6 years and older: 1 tablet or 2 teaspoonfuls daily (or 1 teaspoonful twice daily).Children 2-6 years: 1 teaspoonful once daily or 1/2 teaspoonful twice daily.Children 6 months to 2 years : 1/2 teaspoonful once daily. The dose in children 12-23 months of age can be increased to a maximum dose as 1/2 teaspoonful every 12 hours.

Interaction of Acitrin 10 mg
No clinically significant drug interactions have been found with Theophylline, Azithromycin, Pseudoephedrine, Ketoconazole or Erythromycin and with other drugs.

Contraindications
It is contraindicated in patients with a history of hypersensitivity to Cetirizine or hydroxyzine.

Side Effects of Acitrin 10 mg
The most common side effects that occurred more frequently on Cetirizine is somnolence.

Pregnancy and Lactation
US FDA Pregnancy Category of Cetirizine Hydrochloride is B. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Cetirizine Hydrochloride has been shown to be excreted in human milk. So, caution should be exercised when Cetirizine Hydrochloride is administered to a nursing woman.

Precautions and Warnings
Caution should be exercised when driving a car or operating a heavy machinery.

Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.